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DNA Sequencing: Emerging Technologies and Applications

DNA sequencing services market valued at US$2Bn in 2013


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2014-03-20 14:19:01 - DNA Sequencing: Emerging Technologies and Applications - a new market research report on companiesandmarkets.com

The sequencing services market is expected to grow to nearly $2.0 billion in 2013 and nearly $7.5 billion in 2018, with a CAGR of 30.3%.

The sequencing instruments and consumables market is expected to reach to nearly $1.9 billion in 2013 and nearly $2.9 billion in 2018, with a CAGR of 8.7%.

The global market for DNA sequencing products and services was valued at $3.5 billion in 2012 and was estimated at nearly $4.5 billion for 2013. Anaysts expect the market to grow to nearly $11.7 billion by 2018, and register a five-year compound annual growth rate of 21.2% from 2013 to 2018.

The Human Genome Project (HGP) moved DNA sequencing technology to the forefront of life science research as a genetic analysis

 

 

tool. HGP relied heavily on Sanger sequencing by capillary electrophoresis to decipher the DNA sequence of the bases in the human genome. Consequently, it led to significant improvements in the efficiency and costs of DNA sequencing. During this time period, the sequencing industry consolidated, resulting in one dominant company, Applied Biosystems (now Life Technologies).

Beginning in 2005, the launch of next-generation sequencing (NGS) technologies radically changed the structure of the industry and opened up exciting new market applications. The costs of sequencing have rapidly reduced to the point where it is now feasible for complex NGS tests to be priced in the range of other multiplex genetic tests. As a result, opportunities for sequencing products and services are emerging in diverse applications ranging, for example, from clinical diagnostics to direct to consumer genetic testing markets.

Clinical value has been shown for many applications, and several launched tests are having good commercial success. This shows that both patients and physicians are recognizing the value of NGS tests. At the same time, payors and insurance companies are beginning to provide coverage for these tests, further enhancing their commercial potential. In direct to consumer genetic testing market, there is an emerging trend to move to sequencing of specific genome regions. Compared with microarrays, sequencing provides more comprehensive information to the consumer. These technical and market factors are driving the sequencing markets and it is now timely to examine this market and these factors in detail.

The Human Genome Project (HGP) moved DNA sequencing technology to the forefront of life science research as a genetic analysis tool. The HGP relied heavily on Sanger sequencing by capillary electrophoresis to decipher the DNA sequence of the bases in the human genome.

The HGP led to significant improvements in the efficiency and costs of DNA sequencing. During this time period, the sequencing industry consolidated, resulting in one dominant company, Applied Biosystems (now Life Technologies).

Beginning in 2005, the launch of next-generation sequencing technologies radically changed the structure of the industry and opened up exciting new market applications. The costs of sequencing have rapidly reduced to the point where it is now feasible for complex NGS tests to be priced in the range of other multiplex genetic tests.

As a result, opportunities for sequencing products and services are emerging in diverse applications ranging, for example, from clinical diagnostics to direct to consumer genetic testing markets.

Clinical value has been shown for many applications, and several launched tests are having good commercial success. This shows that both patients and physicians are recognizing the value of NGS tests. Several molecular genetic tests that have been successful on non-NGS formats will run on NGS platforms in the future.

At the same time, payors and insurance companies are beginning to provide coverage for these tests, further enhancing their commercial potential.

In direct to consumer genetic testing market, there is an emerging trend to move to sequencing of specific genome regions. Compared with microarrays, sequencing provides more comprehensive information to the consumer. Recent product introductions by Full Genomes Corporation and Family Tree DNA using NGS to sequence the full Y chromosome are examples of this trend.

These technical and market factors are driving this market so that it is now timely to examine the sequencing markets.

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