EpiCast Report: Dry Eye Syndrome - Epidemiology Forecast to 2022 - a new market research report on companiesandmarkets.com
PR-Inside.com: 2014-03-03 05:53:03
Dry eye syndrome is one of the most common ophthalmological disorders, causing chronic discomfort in up to 100 million people worldwide, and the disease burden is forecast to increase as the average life expectancy rises. The prevalence of dry eye syndrome, also known as keratoconjunctivitis sicca, primarily increases with age, and has an estimated incidence of 15% in persons over the age of 65 years. However, gender, certain medical conditions, and modern conveniences can all play a part in a sufferers condition.
As people grow older the production of oil in the body decreases, which reduces tear production and increases evaporation of tears, resulting in dryness of eyes. A greater risk of acquiring dry eye is also experienced by females, with postmenopausal women being particularly at risk, and again, natural biological changes are the reason for this. Sex hormones are known to play a significant role in ocular surface homeostasis, and studies are investigating how disturbances to this homeostasis may result in dry eye syndrome. Anti-androgen therapy, SjÃ¶grens syndrome, and premature ovarian failure are also associated with androgen deficiency, and may increase the risk for dry eye syndrome, alongside hormone replacement therapy (HRT), which is commonly used among post-menopausal women. Autoimmune diseases and refractive surgeries are also factors which can lead to dry eye syndrome.
Contact lens usage and certain medications can induce or exacerbate dry eye symptoms, including some eye medications, and some systemic medications, such as diuretics, antihistamines, anti-cholinergics, anti-depressants, and systemic retinoids, as these drugs reduce the water and mucous production in the eyes. A low intake of omega-3 fatty acids is also a risk factor for dry eye syndrome; researchers hypothesize that omega-3 fatty acids may have a direct effect on the polar portion of the lipid layer of tear film of the eye.
In addition, exposure to certain environmental conditions, such as excessive wind, extreme temperatures, low relative humidity, air pollution, and smoking, can increase the risk of developing dry eye syndrome. Modern lifestyle changes, such as exposure to air conditioners and television and computer screens can also reduce the blinking rate of the eyes and cause a condition known as episodic dry eye syndrome.
It is expected that the number of prevalent cases of dry eye syndrome throughout the US, France, Germany, Italy, Spain, the UK, Japan, China, and India will grow by 2.73% each year, from 195.64 million cases in 2012 to 249.09 million cases by 2022. China will have the largest number of prevalent cases of dry eye syndrome, followed by India.
Dry eye syndrome, also known as keratoconjunctivitis sicca (KCS), is a multi-factorial disease of the eye caused by dryness, decreased tear production, or increased tear film evaporation. It results in symptoms of discomfort such as visual disturbance and tear film instability (DEWS, 2007). Middle-aged and older adults are the most commonly affected group because of the high prevalence of contact lens usage, systemic drug effects, autoimmune diseases, and refractive surgeries in these group (Davis, 2003; Glasson et al., 2003; Schaumberg et al., 2002; Schaumberg et al., 2003; Toda et al., 2001).
Globally, dry eye has a prevalence of up to 33% (Clegg et al., 2006; Lemp et al., 2008; Schaumberg et al., 2002; Shimmura et al., 1999). The prevalence of dry eye is estimated to range from 30% in various ages groups worldwide (Clegg et al., 2006; Lemp et al., 2008; Shimmura et al., 1999). Research also shows that dry eye syndrome is more prevalent in women than in men (Schaumberg et al., 2002).
- The Dry Eye Syndrome, EpiCast Report provides an overview of the risk factors and global trends of dry eye syndrome in the nine major markets (US, France, Germany, Italy, Spain, UK, Japan, China, and India).
- It also includes a 10-year epidemiology forecast of the prevalent cases of dry eye syndrome, segmented by age (given in five-year increments beginning at age 45 years and ending at ages 85 years and older), sex, and severity in these markets.
Reasons to buy
- Develop business strategies by understanding the trends shaping and driving the global dry eye syndrome market.
- Quantify patient populations in the global dry eye syndrome market to improve product design, pricing, and launch plans.
- Organize sales and marketing efforts by identifying the age groups, sex, and severity levels that present the best opportunities for dry eye syndrome therapeutics in each of the markets covered.
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