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"Monoclonal Antibodies Market in Colorectal Cancer to 2019" is now available at Fast Market Research

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2014-01-03 11:27:46 - Favorable Pricing Policy in the US and Rising Prevalence in Europe and Japan Ensures Market Growth

Monoclonal Antibodies Market in Colorectal Cancer to 2019 -


GBI Research, has released the pharma report "Monoclonal Antibodies Market in Colorectal Cancer to 2019 - ". There are currently three monoclonal Antibody (mAb) treatments approved for metastatic colorectal cancer with the purpose of extending the patient's lifespan; Avastin, Erbitux and Vectibix. The current market leader is Avastin, which generated revenues of $6.2 billion in 2012 across a number of oncology indications. While compelling late-stage candidates are absent from the current pipeline, the anticipated rise in total prevalence of colorectal cancer in the top eight markets may inspire further investment. Pricing patterns for mAbs are highly favorable in the US, the largest market for colorectal cancer, and patent expirations are not

expected to have a substantial effect on any of the featured markets. As a result of this, GBI Research believes the global market has the potential to grow to a value of $5.5 billion by 2019.

Full Report Details at
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* A brief introduction to colorectal cancer, including the disease's pathogenesis, etiology, diagnosis and treatment algorithms.
* In-depth analysis of the three mAbs marketed for colorectal cancer, including analysis of their safety, efficacy, treatment patterns and strengths/weaknesses. Including a heat map comparing the drugs in terms of safety and efficacy.
* A comprehensive review of the pipeline for colorectal cancer therapies, including individual analysis of a number of late-stage pipeline drugs that are likely to enter the market during the forecast period. The pipeline is analyzed on the basis of phase distribution, molecule types, program types, mechanisms of action and molecular targets.
* Additional in-depth analysis of pipeline drug clinical trials by phase, trial size, trial duration and program failure rate for each molecule type, in addition to an in-depth analysis of clinical trial primary endpoints.
* Multi-scenario forecast data of the market to 2019, taking into account how the market may be affected by the introduction of new drugs, the expiry of key patents on current drugs and the changes in disease epidemiology across the key developed markets.
* Discussion of the drivers and barriers for market growth.
* In-depth analysis of all licensing and co-development deals that have occurred in the colorectal cancer market since 2006.

Reasons to Get this Report

* Understand the role of mAbs in the treatment of colorectal cancer and their relation to chemotherapies and targeted small molecule therapies.
* Understand the vast scope of the pipeline, including which molecule types and mechanisms of action are prominent.
* Observe the trends in clinical trial duration and size amongst clinical phases and molecule types. Use the clinical trial failure rate analysis to assess the risk profiles of current and/or future developmental programs for colorectal cancer therapeutics.
* Observe the shift in clinical trial endpoints throughout clinical phases of development, and use this data to potentially influence any future developmental programs.
* Assess the potential clinical and commercial impact of current late-stage pipeline molecules in the colorectal cancer mAbs market.

Partial Table of Contents:

1 Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Monoclonal Antibodies in Colorectal Cancer Market to 2019 - Introduction
2.1 Symptoms
2.2 Etiology
2.3 Epidemiology
2.4 Pathophysiology
2.5 Diagnosis
2.6 Prognosis and Disease Staging
2.7 Treatment Options
2.7.1 Chemotherapy
2.7.2 Targeted Therapies
2.7.3 Resistance to Pharmacological Therapies
2.7.4 Treatment Guidelines
3 Monoclonal Antibodies in Colorectal Cancer Market to 2019 - Marketed Products
3.1 Avastin (Bevacizumab) - Hoffman La Roche
3.2 Erbitux (Cetuximab) - Bristol-Myers Squibb, Eli Lilly, and Merck KGaA
3.3 Vectibix (Panitumumab) - Amgen and Takeda
3.4 Heat Map for Marketed Products
3.5 Conclusion
4 Monoclonal Antibodies in Colorectal Cancer Market to 2019 - Developmental Pipeline
4.1 Overall Pipeline
4.2 Molecular Targets and Mechanisms of Action
4.3 Clinical Trials
4.3.1 Failure Rate
4.3.2 Clinical Trial Size
4.3.3 Duration
4.3.4 Primary Endpoints
4.4 Conclusion
4.5 Key Late-Stage Pipeline Products
4.5.1 IMC-1121B (Ramucirumab) - Eli Lilly and Company
4.5.2 Xilonix - XBiotech
4.5.3 MetMAb (Onartuzumab) - Hoffmann-La Roche
4.5.4 Anti-DR5 MoAb (Tigatuzumab) - Daiichi Sankyo
4.5.5 MK0646 (Dalotuzumab) - Merck
4.5.6 AMG-655 (Conatumumab) - Amgen
4.6 Conclusion
5 Monoclonal Antibodies in Colorectal Cancer Market to 2019- Market Forecast to 2019
5.1 Global
5.1.1 Treatment Usage Patterns
5.1.2 Market Size
5.2 North America
5.2.1 US
5.2.2 Canada
5.3 Europe
5.3.1 Treatment Usage Patterns
5.3.2 Annual Cost of Therapy
5.3.3 Market Size
5.4 Japan
5.4.1 Treatment Usage Patterns
5.4.2 Market Size
5.5 Drivers and Barriers
5.5.1 Drivers
5.5.2 Barriers
6 Monoclonal Antibodies in Colorectal Cancer Market to 2019- Deals and Strategic Consolidations
6.1 R&D Licensing Agreements
6.1.1 Key Licensing Deals
6.2 Co-Development Agreements
6.2.1 Key Co-Development Agreements
7 Monoclonal Antibodies in Colorectal Cancer Market to 2019- Appendix
7.1 Market Definitions
7.2 Abbreviations
7.3 References
7.4 Sources for Heat Map
7.5 All Pipeline Products, by Stage of Development
7.5.1 Discovery
7.5.2 Preclinical and IND/CTA-filed
7.5.3 Phase I

Full Table of Contents is available at:

About GBI Research

GBI Research provides industry-leading global business intelligence solutions. Their products and services help companies make better business decisions, win business and position themselves more effectively. GBI Research publishes more than 100 research reports each year across a wide range of industries. These reports draw on in-depth primary and secondary research, databases of proprietary in-house data and high quality analysis from their expert teams. GBI Research employs hundreds of highly qualified Analysts across the US, Europe and Asia. View more research from GBI Research at

About Fast Market Research

Fast Market Research is an online aggregator and distributor of market research and business information. We represent the world's top research publishers and analysts and provide quick and easy access to the best competitive intelligence available.

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