2014-01-09 18:04:01 - EpiCast Report: Gram-Negative Bacterial Urinary Tract Infection - Epidemiology Forecast to 2022 - a new market research report on companiesandmarkets.com
Urinary tract infections (UTIs) are among the most common bacterial infections acquired in hospitals and in the community setting (Foxman, 2010). Globally, an estimated 150 million UTIs occur annually, resulting in over six billion dollars in direct healthcare expenditures (Stamm and Norrby, 2001). In the US alone, UTI results in nearly seven million office visits, and one million emergency department visits each year (Foxman, 2002). A UTI can occur when daily living activities and medical interventions aid in the movement of bacteria into the urethra; however, bacterial colonization does not always lead to the development of UTI symptoms (Foxman, 2010).
Although UTIs can be caused by bacteria, viruses, or fungi, gram-negative bacteria are the pathogens most frequently associated with UTIs (Gaynes
et al., 2005). Gram-negative bacteria have become increasingly resistant to individual antimicrobials, and of particular concern, is the emergence of multidrug-resistant activity in these organisms (D´Agata, 2004). Although there has been little change in the predominant causative pathogens in the past few decades, individual pathogen frequency and resistance patterns of gram-negative pathogens vary considerably between settings, countries, and continents (Gupta et al., 2001; Ortega et al., 2013; Ronald, 2002; Shigemura et al., 2005).
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