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New Market Research Report: Zometa (Prostate Cancer) - Forecast and Market Analysis to 2022

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2013-02-27 03:25:44 - New Pharmaceuticals research report from GlobalData is now available from Fast Market Research

GlobalData has released its new PharmaPoint Drug Evaluation report, "Zometa (Prostate Cancer) - Forecast and Market Analysis to 2022". The recent approvals of second-line metastatic castration-resistant prostate cancer (mCRPC) therapies like J&J's Zytiga (abiraterone acetate) and Medivation/Astellas' Xtandi (enzalutamide) will drive strong market growth over the next decade. These safe and orally administered treatments will provide safety and convenience benefits over the current standard of care, chemotherapy with docetaxel, while prolonging the overall survival of patients with mCRPC. The December 12, 2012 FDA approval of Zytiga for the added indication of chemotherapy-naive mCRPC marks the onset of a new treatment paradigm for the disease, in which chemotherapy is relegated to second-line therapy and beyond. For patients with earlier-stage prostate cancer,

androgen deprivation therapy with LHRH agonists and first-generation antiandrogens remains the standard of care for suppressing testosterone levels and temporarily controlling the disease.

Full Report Details at
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Novartis' Zometa is a bisphosphonate indicated for the treatment of bone metastases in patients with CRPC, other solid tumors, and multiple myeloma. Its active ingredient, zoledronic acid, inhibits osteoclastic activity and induces apoptosis in osteoclasts, the cells responsible for bone resorption (Zometa Prescribing Information, 2012). This helps prevent the SREs that are a common symptom of bone metastases. Zometa has also been shown to inhibit the increase in osteoclast activity resulting from various stimulatory factors released by tumors. Although Zometa has been a blockbuster, worldwide patent expiries between 2012 and 2013 will open the door for generic competition and undoubtedly erode its sales (Novartis Annual Report, 2011).


* Overview of Prostate cancer, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
* Detailed information on Xgeva including product description, safety and efficacy profiles as well as a SWOT analysis.
* Sales forecast for Xgeva for the top nine countries from 2012 to 2022.
* Sales information covered for the US, Japan, UK, France, Germany, Spain, Italy , Canada, and Australia

Reasons to buy

* Understand and capitalize by identifying products that are most likely to ensure a robust return
* Stay ahead of the competition by understanding the changing competitive landscape for Prostate cancer
* Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
* Make more informed business decisions from insightful and in-depth analysis of Xgeva performance
* Obtain sales forecast for Xgeva from 2012-2022 in nine markets (US, Japan, UK, France, Germany, Spain, Italy , Canada, and Australia)

Report Table of Contents:

1 Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Introduction
2.1 Catalyst
2.2 Related Reports
2.3 Upcoming Related Reports
3 Disease Overview
3.1 Etiology and Pathophysiology
3.1.1 Etiology
3.1.2 Pathophysiology
3.1.3 Prognosis
3.1.4 Quality of Life
3.2 Symptoms
4 Disease Management
4.1 Diagnosis and Referral Overview
4.2 Treatment Overview
4.2.1 Conservative Management Strategies
4.2.2 Localized Treatments
4.2.3 Hormone Therapy
4.2.4 Drug Therapies
5 Competitive Assessment
5.1 Overview
5.2 Strategic Competitor Assessment
6 Zometa (zoledronic acid)
6.1 Overview
6.2 Efficacy
6.3 Safety
6.4 SWOT Analysis
6.5 Forecast
7 Appendix
7.1 Bibliography
7.2 Abbreviations
7.3 Methodology
7.4 Forecasting Methodology
7.4.1 Number of Prostate Cancer Patients Currently Seeking Treatment
7.4.2 Percent Drug-treated Patients
7.4.3 Percent Hormone Therapy-Treated Patients
7.4.4 General Pricing Assumptions
7.4.5 Individual Drug Assumptions
7.4.6 Generic Erosion
7.5 Physicians and Specialists Included in This Study
7.6 Survey of Prescribing Physicians
7.7 About the Authors
7.7.1 Authors
7.7.2 Global Head of Healthcare
7.8 About GlobalData
7.9 Contact Us
7.10 Disclaimer

List of Tables

1.1 List of Tables
Table 1: Stage Distribution of Prostate Cancer at Diagnosis in Selected Major Markets
Table 2: Global Variations in Recommendations on Routine PSA Screening
Table 3: Most Commonly Followed Treatment Guidelines for Prostate Cancer, 2012
Table 4: Most Commonly Prescribed Drugs for Prostate Cancer by Class in the Global Markets, 2012
Table 5: Leading Treatments for Prostate Cancer, 2012
Table 6: Product Profile - Zometa
Table 7: Zometa SWOT Analysis, 2012
Table 8: Global Sales Forecasts ($m) for Zometa, 2012-2022
Table 9: Physicians Surveyed, By Country

List of Figures

1.2 List of Figures
Figure 1: General Treatment Algorithm for Prostate Cancer, 2012

About GlobalData

GlobalData is a leading provider of global business intelligence including market, competitor, product and customer information. It provides in-depth research, analysis, data and forecasts through a range of interactive online databases, reports and management briefings. GlobalData has a large team of experienced research and analysis, consulting, and marketing experts. It has a global presence, including key offices in the US, Europe and Asia. The group has over 50 years of experience of delivering market intelligence data and analysis and a highly experienced senior management team. View more research from GlobalData at

About Fast Market Research

Fast Market Research is an online aggregator and distributor of market research and business information. We represent the world's top research publishers and analysts and provide quick and easy access to the best competitive intelligence available.

For more information about these or related research reports, please visit our website at or call us at 1.800.844.8156.

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