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Orencia (Systemic Lupus Erythematosus and Lupus Nephritis) - Forecast and Market Analysis to 2022 - New Market Report

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2013-12-13 10:47:23 - Fast Market Research recommends "Orencia (Systemic Lupus Erythematosus and Lupus Nephritis) - Forecast and Market Analysis to 2022" from GlobalData, now available

Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease that can affect any organ or tissue and is the prototypic autoimmune disease. While SLE can affect multiple major organ systems in the body, one of its most severe manifestations includes renal (kidney) involvement, known as lupus nephritis (LN). The term LN refers to SLE patients with glomerulonephritis, and when the term LN is used, glomerular tissue injury in the kidneys is always involved. Renal injury without any glomerular involvement is classified as nephritis in a patient with SLE.

Orencia (abatacept) is a marketed drug for the treatment of RA and polyarticular juvenile idiopathic arthritis. It was developed by Bristol-Myers Squibb (BMS) and is being evaluated as a potential treatment for

patients with LN.


* Overview of SLE-LN, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
* Detailed information on Orencia including product description, safety and efficacy profiles as well as a SWOT analysis.
* Sales forecast for Orencia for the top seven countries from 2012 to 2022.
* Sales information covered for the US, France, Germany, Italy, Spain, the UK and Japan

Full Report Details at
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Reasons to Get this Report

* Understand and capitalize by identifying products that are most likely to ensure a robust return
* Stay ahead of the competition by understanding the changing competitive landscape for SLE-LN
* Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
* Make more informed business decisions from insightful and in-depth analysis of Orencia performance
* Obtain sales forecast for Orencia from 2012-2022 in top seven countries (the US, France, Germany, Italy, Spain, the UK and Japan)

Report Table of Contents:

1 Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Introduction
2.1 Catalyst
2.2 Related Reports
3 Disease Overview
3.1 Etiology and Pathophysiology
3.1.1 Etiology
3.1.2 Pathophysiology
3.2 Prognosis
3.3 Quality of Life
3.4 Symptoms
4 Disease Management
4.1 Diagnosis Overview
4.1.1 SLE Diagnosis
4.1.2 LN Diagnosis
4.2 Treatment Overview
5 Competitive Assessment
5.1 Overview
5.2 Strategic Competitor Assessment
6 Opportunity and Unmet Need
6.1 Overview
6.2 Unmet Needs
6.2.1 Efficacious Treatments with Reduced Side Effects
6.2.2 Management of LN
6.2.3 Improvement in Patients' Mortality
6.2.4 Management of Lupus Comorbidities
6.2.5 Sensitive and Reliable Biomarkers
6.2.6 Physicians' Education and Public Awareness of SLE
6.2.7 Unmet Needs Gap Analysis
6.3 Opportunities
6.3.1 Efficacious and Safe Therapies
6.3.2 Therapies Targeting LN Patients
6.3.3 Treatments for Common Lupus Comorbidities
6.3.4 Discovery of Biomarkers
7 Pipeline Assessment
7.1 Overview
7.2 Promising Drugs in Clinical Development
8 Orencia (abatacept)
8.1 Overview
8.2 Efficacy
8.3 Safety
8.4 Dosing and Formulation
8.5 Potential Clinical Positioning
8.6 Potential Commercial Positioning
8.7 Pricing and Reimbursement
8.8 SWOT Analysis
8.9 Forecast
9 Appendix
9.1 Bibliography
9.2 Abbreviations
9.3 Methodology
9.4 Forecasting Methodology
9.4.1 Diagnosed SLE and LN Patients
9.4.2 Percent Drug-Treated Patients
9.4.3 General Pricing Assumptions
9.4.4 Generic Erosion
9.4.5 Pricing of Pipeline Agents
9.5 Physicians and Specialists Included in this Study
9.6 Primary Research - Prescriber Survey
9.7 About the Authors
9.7.1 Analysts
9.7.2 Global Head of Healthcare
9.8 About GlobalData
9.9 Disclaimer

List of Tables

1.1 List of Tables
Table 1: Symptoms of SLE
Table 2: 1997 Updated ACR Criteria for Classification of SLE
Table 3: The SLICC Clinical and Immunologic Criteria for Classification of SLE
Table 4: WHO and ISN/RPS classifications of LN
Table 5: Treatment Guidelines for SLE and LN
Table 6: Most Prescribed Drugs for SLE and LN by Class in the Global Markets, 2013
Table 7: Leading Treatments for SLE and LN, 2013
Table 8: Overall Unmet Needs in SLE and LN - Current Level of Attainment
Table 9: Clinical Unmet Needs in SLE and LN - Gap Analysis, 2013
Table 10: SLE and LN - Phase Pipeline, 2013
Table 11: Comparison of Therapeutic Classes in Development for SLE and LN, 2013
Table 12: Product Profile - Orencia
Table 13: Orencia SWOT Analysis, 2013
Table 14: Global SLE Sales Forecasts ($m) for Orencia, 2012-2022
Table 15: Global LN Sales Forecasts ($m) for Orencia, 2012-2022
Table 16: Number of Physicians Surveyed by Country

List of Figures

1.2 List of Figures
Figure 1: Overview of the Etiology and Pathogenesis of SLE
Figure 2: Overview of the BAFF/APRIL Ligand and Receptor System
Figure 3: Overview of the Treatment Management of SLE
Figure 4: Competitive Assessment of Late-Stage Pipeline Agents in SLE and LN, 2012-2022

About GlobalData

GlobalData is a leading provider of global business intelligence including market, competitor, product and customer information. It provides in-depth research, analysis, data and forecasts through a range of interactive online databases, reports and management briefings. GlobalData has a large team of experienced research and analysis, consulting, and marketing experts. It has a global presence, including key offices in the US, Europe and Asia. The group has over 50 years of experience of delivering market intelligence data and analysis and a highly experienced senior management team. View more research from GlobalData at

About Fast Market Research

Fast Market Research is an online aggregator and distributor of market research and business information. We represent the world's top research publishers and analysts and provide quick and easy access to the best competitive intelligence available.

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